Last data update: May 13, 2024. (Total: 46773 publications since 2009)
Records 1-3 (of 3 Records) |
Query Trace: Williams RJ[original query] |
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Chemical Composition of JUUL Pods Collected From Students in California High Schools
Shamout M , Wang P , Wong F , Chen W , Kumagai K , Pérez JJ , Watson CH , Valentín-Blasini L , Tanz L , Herzig C , Oakley LP , Peak CM , Heinzerling A , Williams RJ , Hess C , Wang C , Planche S , Al-Shawaf M , Melstrom P , Marynak K , Tynan MA , Agaku IT , King BA . J Adolesc Health 2021 69 (2) 342-345 PURPOSE: To examine the chemical composition of JUUL pods collected from a convenience sample of 16 high schools in California to identify possible consumer modification or counterfeit use. METHODS: Using Gas Chromatography-Mass Spectrometry, we quantitatively analyzed the nicotine, propylene glycol (PG), and vegetable glycerin (VG) in JUUL pods (n = 26) collected from California high schools and compared results to commercial 3% (n = 15) and 5% (n = 24) JUUL pods purchased online. RESULTS: Most of the collected JUUL pods (24/26 pods) had a nicotine concentration (43.3 mg/ml, 95% PI: 21.5-65.1) outside the prediction intervals (PI) of the 3% (33.5 mg/ml, 95% PI: 31.8-35.2) and 5% (55.0 mg/ml, 95% PI: 51.5-58.3) commercial JUUL pods. Most (73%) collected JUUL pods had VG concentrations (583.5 mg/ml, PI: 428.9-738.1) lower than the 3% (722.2 mg/ml, PI: 643.0-801.4) and 5% (710.5 mg/ml, PI: 653.1-767.8) commercial JUUL pods. CONCLUSIONS: Used JUUL products collected from high school students or found on school grounds were not chemically consistent with the manufacturer's stated formulations. |
Notes from the field: Characteristics of e-cigarette, or vaping, products confiscated in public high schools in California and North Carolina - March and May 2019
Shamout M , Tanz L , Herzig C , Oakley LP , Peak CM , Heinzerling A , Hast M , McGowan E , Williams RJ , Hess C , Wang C , Planche S , Herndon S , Martin J , Kansagra SM , Al-Shawaf M , Melstrom P , Marynak K , Tynan MA , Agaku IT , King BA . MMWR Morb Mortal Wkly Rep 2020 69 (42) 1552-1554 E-cigarette, or vaping, products are electronic devices that produce an inhalable aerosol by heating an e-liquid that typically contains nicotine and other additives (1). Nicotine is highly addictive, can harm adolescent brain development, and can prime the brain for addiction to other drugs (1). In 2019, 27.5% of U.S. high school students currently used e-cigarettes (2), and 73.4% of high school students had observed e-cigarette use on school grounds (3). E-cigarette use among U.S. youths increased considerably during 2017–2019 (2). This rise coincided with the increased popularity of “pod mods,” which are products with a prefilled or refillable pod cartridge (pod) and a modifiable (mod) system. Pod mods typically use nicotine salts rather than the freebase nicotine used in most other e-cigarette, or vaping, products and conventional tobacco products (e.g., cigarettes).* Nicotine salts, which have a lower pH than freebase nicotine, allow particularly high levels of nicotine to be inhaled more easily and with less irritation to the throat than freebase nicotine.† The most commonly sold pod mod brand is JUUL, which accounted for 75% of all U.S. e-cigarettes sales by the end of 2018.§ A majority (59.1%) of U.S. high school student e-cigarette users report JUUL is their usual brand (2). |
Trace metals screening process of devices used for the collection, analysis, and storage of biological specimens
Ward CD , Williams RJ , Mullenix K , Syhapanha K , Jones RL , Caldwell K . At Spectrosc 2018 39 (6) 219-228 The Centers for Disease Control and Prevention’s (CDC) Environmental Health Laboratory uses modified versions of inductively coupled plasma mass spectrometry (ICP-MS) analytical methods to quantify metals contamination present in items that will come into contact with patient samples during the preanalytical, analytical, and postanalytical stages. This lot screening process allows us to reduce the likelihood of introducing contamination which can lead to falsely elevated results. This is particularly important when looking at biomonitoring levels in humans which tend to be near the limit of detection of many methods. The fundamental requirements for a lot screening program in terms of facilities and processes are presented along with a discussion of sample preparation techniques used for lot screening. The criteria used to evaluate the lot screening data to determine the acceptability of a particular manufacturing lot is presented as well. As a result of lot testing, unsuitable manufactured lots are identified and excluded from use. |
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